Researchers from Anglia Ruskin University (ARU) have conducted a study revealing concerning potential dangers associated with neotame, a relatively new artificial sweetener commonly found in various food and beverage products. Neotame is used in cakes, drinks, chewing gum, and other consumer goods.
The study, published in the journal Frontiers in Nutrition, suggests that neotame can directly harm the protective lining of the gut and disrupt the balance of gut bacteria. This disruption can weaken the gut barrier, leading to digestive issues, compromised immunity, and potentially serious health conditions such as sepsis.
According to Dr. Chichger, Associate Professor in Biomedical Science at ARU and senior author of the study, the research demonstrates that neotame causes cell death in epithelial cells lining the intestines. These cells play a crucial role in maintaining a barrier between the gut contents and the bloodstream. The death of these cells weakens the barrier, potentially allowing harmful substances to enter the bloodstream.
Additionally, neotame may disrupt the balance of gut bacteria, causing normally beneficial bacteria to become harmful. This disruption can lead to increased attachment to the gut wall, invasion of the gut lining, and even translocation into the bloodstream, raising the risk of sepsis.
The study highlights several potential health consequences of neotame consumption, including:
Irritable Bowel Syndrome (IBS): Damage to the gut barrier can trigger inflammation and exacerbate symptoms of IBS, such as bloating, pain, and diarrhea.
Sepsis: A compromised gut barrier allows harmful bacteria to enter the bloodstream, increasing the risk of life-threatening sepsis.
Metabolic and Inflammatory Disorders: An altered gut microbiome may contribute to insulin resistance, chronic inflammation, and the development of chronic diseases.
The findings of this study contribute to growing concerns about the safety of artificial sweeteners. While these sweeteners offer a sugar-free alternative, their potential impact on gut health warrants further investigation. The long-term consequences of consuming neotame and other artificial sweeteners remain a significant health concern.
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