In a joint international study, researchers from Australia, Denmark, and Finland examined the differences between people of the same race and different types of food. .
Flies were given six different foods that contain a lot of protein, sugar, starch, coconut oil or fiber, or a combination of sugar and fiber. The species used in the study had their own genetic makeup, which made it possible to combine the differences observed in specific genetic tests.
Studies have shown that genetic variants in flies’ ability to utilize different energy sources to eat healthy foods. said EssiHavula, now a postdoctoral researcher at the University of Helsinki.”The genes that control the body are well-preserved in evolution, which is why we can learn more about the digestion of food in the human body by research done by flies,” added Havula.
Researchers have obtained genetic analysis
In genetic analysis, the researchers found a number of genes that contributed to the fly’s ability to tolerate sugar. Many of these genes are also found in humans and have been suggested in previous studies of a broader genetic organization to contribute to obesity and type 2 diabetes. ), previously investigated primarily for the functioning and development of the nervous system, is necessary.
In addition, researchers have shown that the JNK method, one of the most important mechanisms of stress, regulates sugar metabolism and fat storage in the form of high-sugar diets in the study. “It seems that eating sugar causes stress on the cells, which gives the JNK method an important role in the way flies tolerate and process sugar,” said Havula.
How to recommend the same food
According to researchers, most of the findings could be applied to humans, although further research is needed. Havula points out that research provides concrete evidence of how similar dietary recommendations do not suit everyone.
“Research-based data also show how metabolic responses to food differ between animals and individuals. Recommendations for a regular diet are not suitable for everyone, which explains the ongoing lack of consensus on ‘healthy eating’.” by organizing nutritious foods based on individual genetic information. This will be less expensive than medication and will improve a person’s health over time, ”said Havula.
Source Journal Reference: E. Havula, S. Ghazanfar, N. Lamichane, D. Francis, K. Hasygar, Y. Liu, L. A. Alton, J. Johnstone, E. J. Needham, T. Pulpitel, T. Clark, H. N. Niranjan, V. Shang, V. Tong, N. Jiwnani, G. Audia, A. N. Alves, L. Sylow, C. Mirth, G. G. Neely, J. Yang, V. Hietakangas, S. J. Simpson, A. M. Senior. Genetic variation of macronutrient tolerance in Drosophila melanogaster. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-29183-x
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